Influence of biological and analytical variation on urine measurements for monitoring exposure to cadmium

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Influence of biological and analytical variation on urine measurements for monitoring exposure to cadmium.

OBJECTIVE To define the mean intraindividual biological variation in urinary concentrations of cadmium and retinol binding protein (RBP) in untimed, random urine samples and the influence of creatinine or specific gravity correction on reducing this variation. The relation between biological variation and analytical variation in defining uncertainty in a single measurement and significant diffe...

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Biological variation in urine samples used for analyte measurements.

To determine the influence of biological variation on the reliability of data from different types of urine specimens, we measured nine analytes in first-morning, randomly collected, and 24-h samples of urine from 53 healthy individuals (14 men and 39 women). The urines were collected once a week for 10 weeks. The data obtained were used as a basis for specimen collection and to gain insight in...

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Assessment of exposure to lead through air and biological monitoring in a lead and zinc mine

 Background and aim: Lead is ubiquitous and one of the earliest metals discovered by the human. This metal is widely used in different industries due to its important physico-chemical properties like softness, high malleability, ductility, low melting point and resistance to corrosion. Lead absorbed in body with several routs and when transfer in blood is primarily in red blood cells. Human exp...

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Biological monitoring of genotoxicity to organophosphate pesticide exposure among rice farmers: Exposure-effect continuum study

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Breath, urine, and blood measurements as biological exposure indices of short-term inhalation exposure to methanol.

Due to their transient nature, short-term exposures can be difficult to detect and quantify using conventional monitoring techniques. Biological monitoring may be capable of registering such exposures and may also be used to estimate important toxicological parameters. This paper investigates relationships between methanol concentrations in the blood, urine, and breath of volunteers exposed to ...

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ژورنال

عنوان ژورنال: Occupational and Environmental Medicine

سال: 1998

ISSN: 1351-0711

DOI: 10.1136/oem.55.2.132